Pontificia Universidad Javeriana, Hospital Universitario San Ignacio, Bogotá, Colombia.
Pontificia Universidad Javeriana, Hospital Universitario San Ignacio, Bogotá, Colombia.
Diabetes Res Clin Pract. 2011 Aug;93(2):243-247. doi: 10.1016/j.diabres.2011.05.002. Epub 2011 May 31.
The recent definitions of the metabolic syndrome (MS) recognize the need for ethnic and region-specific waist circumference (WC) cut-offs that identify people with abdominal obesity. We tested WC as a diagnostic tool to identify people with visceral adiposity in Hispanics from the Latin America region.
We used the area of visceral adipose tissue (VAT) ≥ 100 cm² at the level between the 4th and 5th lumbar vertebrae in abdominal CT scans as a marker of visceral adiposity and established the optimal WC threshold for men and women by means of receiver operating characteristic (ROC) curves.
179 men and 278 women from Mexico, El Salvador, Venezuela, Colombia and Paraguay were included. The ROC curves were highly discriminative of excess VAT for men and women (area under the curve 0.9 and 0.8 respectively) and the WC threshold was identified at 94 cm for men and between 90 and 92 cm for women.
In men the WC cutoff was equal to that proposed for europids and suggested for US adults who may have strong genetic contribution to insulin resistance such as Hispanics. In women the threshold was significantly higher than previously proposed for South and Central Americans.
代谢综合征(MS)的最新定义认识到需要根据种族和地区特异性腰围(WC)切点来识别有腹部肥胖的人群。我们检测了 WC 作为一种诊断工具,以识别拉丁美洲地区西班牙裔人群中的内脏肥胖者。
我们使用腹部 CT 扫描第 4-5 腰椎水平处的内脏脂肪组织(VAT)面积≥100cm²作为内脏肥胖的标志物,并通过接受者操作特征(ROC)曲线确定男性和女性的最佳 WC 阈值。
纳入了来自墨西哥、萨尔瓦多、委内瑞拉、哥伦比亚和巴拉圭的 179 名男性和 278 名女性。ROC 曲线对男性和女性的 VAT 过量具有高度的区分能力(曲线下面积分别为 0.9 和 0.8),WC 阈值男性为 94cm,女性为 90-92cm。
在男性中,WC 切点与欧洲人提出的切点以及美国成年人的建议切点相等,这些人可能对胰岛素抵抗有很强的遗传易感性,如西班牙裔。在女性中,该阈值明显高于之前为南美人提出的阈值。