Tsukiyama Hidekazu, Nagai Yoshio, Matsubara Fumiaki, Shimizu Hiroyuki, Iwamoto Teruaki, Yamanouchi Eigoro, Sada Yukiyoshi, Kato Hiroyuki, Ohta Akio, Tanaka Yasushi
Division of Metabolism and Endocrinology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
International University of Health and Welfare Hospital, Nasushiobara, Japan.
J Diabetes Investig. 2016 Jul;7(4):587-93. doi: 10.1111/jdi.12454. Epub 2016 Jan 22.
AIM/INTRODUCTION: Waist circumference (WC) is the most important parameter for diagnosis of metabolic syndrome. The present study was carried out to obtain optimal WC cut-off values for diagnosis of metabolic syndrome in a Japanese population based on the measurement of total intra-abdominal visceral fat volume (VFV), which could be expected to reflect visceral obesity more precisely than visceral fat area.
A total of 405 Japanese persons undergoing health screening were investigated. visceral fat volume was calculated from the data in 700-800 computed tomography slices from the top of the liver to the floor of the pelvic cavity. Then, receiver operating characteristic analysis was used to determine the cut-off value of the VFV/height ratio. Subsequently, the corresponding WC value was obtained by linear regression analysis.
The cut-off value of the VFV/height ratio was 2,317 cm(3) /m in men and 1,425 cm(3) /m in women. The sensitivity and specificity of the ratio were 52.9 and 86.4% in men vs 63.4 and 82.2% in women, respectively. The corresponding cut-off value of WC was 86.0 cm in men and 80.9 cm in women.
The proposed cut-off values of WC for metabolic syndrome are 85 cm in Japanese men and 80 cm in Japanese women.
目的/引言：腰围（WC）是诊断代谢综合征的最重要参数。本研究旨在基于全腹内脏脂肪体积（VFV）的测量，获得日本人群中用于诊断代谢综合征的最佳WC临界值，相较于内脏脂肪面积，VFV有望更精确地反映内脏肥胖。
对405名接受健康筛查的日本人进行了调查。根据从肝脏顶部到盆腔底部的700 - 800层计算机断层扫描数据计算内脏脂肪体积。然后，采用受试者工作特征分析来确定VFV/身高比值的临界值。随后，通过线性回归分析获得相应的WC值。
男性VFV/身高比值的临界值为2317 cm³/m，女性为1425 cm³/m。该比值的敏感性和特异性在男性中分别为52.9%和86.4%，在女性中分别为63.4%和82.2%。相应的WC临界值男性为86.0 cm，女性为80.9 cm。
日本男性代谢综合征的WC建议临界值为85 cm，日本女性为80 cm。
