Snead O C
Department of Neurology, University of Southern California School of Medicine, Children's Hospital, Los Angeles 90027.
Pediatr Neurol. 1990 May-Jun;6(3):147-50. doi: 10.1016/0887-8994(90)90054-5.
Although the syndrome of infantile spasms has been known for 150 years and its treatment described since 1958, controversy still surrounds the appropriate therapy for this devastating disorder. The rationale, dosage, and side effects of ACTH treatment of infantile spasms is described. The recommended treatment regimen is placed in the context of the literature on the therapy of spasms and its relation to outcome.
尽管婴儿痉挛症已被认知达150年之久，且自1958年以来已有关于其治疗的描述，但对于这种严重疾病的恰当治疗方法仍存在争议。本文描述了促肾上腺皮质激素（ACTH）治疗婴儿痉挛症的基本原理、剂量及副作用。所推荐的治疗方案是基于有关痉挛症治疗的文献及其与治疗结果的关系而制定的。
