Robinson R O, Fujimura M, Howat P, Salisbury D M
Arch Dis Child. 1977 Sep;52(9):696-9. doi: 10.1136/adc.52.9.696.
143 fresh blood transfusions were given to 32 low birthweight babies, 28 of whom had hyaline membrane disease. The arterial or central venous pressure was raised by a blood transfusion if before transfusion the mean arterial pressure was less than 35 mmHg or if the diastolic central venous pressure was less than -- 0-5 mmHg. There was no effect of blood transfusion on pH. It therefore appears either that metabolic acidosis in hyaline membrane disease is not caused by poor peripheral perfusion or that blood transfusion does not increase peripheral blood flow in this condition. The safety of the procedure is assessed.
对32名低体重儿进行了143次新鲜输血,其中28名患有透明膜病。如果输血前平均动脉压低于35 mmHg或舒张期中心静脉压低于 - 0.5 mmHg,则输血会使动脉或中心静脉压升高。输血对pH值没有影响。因此,似乎要么透明膜病中的代谢性酸中毒不是由外周灌注不良引起的,要么在这种情况下输血不会增加外周血流。对该操作的安全性进行了评估。