Chavez Temujin T, Fraser Susan L, Kassop David, Bowden Lynden P, Skidmore Peter J
Division of Infectious Diseases, Department of Medicine, National Naval Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20889-5000, USA.
Mil Med. 2011 May;176(5):586-8. doi: 10.7205/milmed-d-10-00346.
Nocardia species are ubiquitous in the environment and can be found worldwide. Direct inhalation remains the most commonly attributed route of infection with Nocardia asteroides complex, causing 50% of invasive infections. Improved molecular methods have identified a significant proportion of N. asteroides complex isolates to be Nocardia cyriacigeorgica. We report a case of a 58-year-old male working as a contractor in Bagram Air Force Base, Afghanistan, with disseminated N. cyriacigeorgica involving the lung, brain, and dermis. Diagnosis was facilitated by early identification of branched, filamentous bacteria using Fite and gram staining along secA DNA sequencing of clinical isolates. Our patient is the first confirmed case of N. cyriacigeorgica infection in Afghanistan.
诺卡菌属在环境中普遍存在，在世界各地都能找到。直接吸入仍然是感染星形诺卡菌复合体最常见的途径，导致50%的侵袭性感染。改进的分子方法已鉴定出相当一部分星形诺卡菌复合体分离株为乔治西里亚克诺卡菌。我们报告了一例58岁男性病例，该男性在阿富汗巴格拉姆空军基地担任承包商，患有播散性乔治西里亚克诺卡菌感染，累及肺、脑和真皮。通过使用菲特染色和革兰氏染色以及临床分离株的secA DNA测序早期鉴定出分支丝状细菌，从而促进了诊断。我们的患者是阿富汗首例确诊的乔治西里亚克诺卡菌感染病例。
