Tsuchiya Yumi, Nakamura Morio, Oguri Tomoyo, Taniyama Daisuke, Sasada Shinji
Department of Pulmonary Medicine, Tokyo Saiseikai Central Hospital, Tokyo, JPN.
Department of Pulmonary Medicine, National Hospital Organization Kanagawa Hospital, Kanagawa, JPN.
Cureus. 2022 Apr 11;14(4):e24023. doi: 10.7759/cureus.24023. eCollection 2022 Apr.
Nocardiosis is a relatively rare opportunistic infection, ranging from localized to systemic diseases, commonly occurring in immunocompromised patients with high mortality rates. We present a case of a 61-year-old man who received medical treatment for type 2 diabetes mellitus and underwent a physical examination that showed abnormal chest shadows on radiography. Chest computed tomography revealed bronchiectasis and infiltration in the left lower lobe. was detected in the bronchial washes, and he was started on sulfamethoxazole-trimethoprim under the diagnosis of pulmonary nocardiosis. 16S ribosomal RNA gene sequencing analysis identified the species as His pulmonary lesions successfully improved after treatment for six months. Pulmonary nocardiosis often presents with symptoms such as hemoptysis and blood-tinged sputum, and bronchiectasis has been identified as an underlying condition. Even in hosts without underlying immunocompromising conditions, can be a causative microorganism of pulmonary infections, and it should be considered in the differential diagnoses.
诺卡菌病是一种相对罕见的机会性感染，范围从局部疾病到全身性疾病，常见于免疫功能低下的患者，死亡率较高。我们报告一例61岁男性病例，该患者因2型糖尿病接受治疗，体检时胸部X线显示有异常阴影。胸部计算机断层扫描显示左下叶支气管扩张和浸润。支气管灌洗中检测到（此处原文缺失相关内容），在诊断为肺诺卡菌病后开始使用磺胺甲恶唑-甲氧苄啶治疗。16S核糖体RNA基因测序分析确定该菌种为（此处原文缺失相关内容）。经过六个月的治疗，他的肺部病变成功改善。肺诺卡菌病常表现为咯血和痰中带血等症状，支气管扩张已被确定为潜在疾病。即使在没有潜在免疫功能低下情况的宿主中，（此处原文缺失相关内容）也可能是肺部感染的致病微生物，在鉴别诊断中应予以考虑。
