Laboratório de Química Metodológica e Orgânica Sintética (LaQMOS), Instituto de Química, Universidade de Brasília, C.P. 4478, 70910-970, Brasília, DF, Brasil.
Org Biomol Chem. 2011 Jul 21;9(14):5024-7. doi: 10.1039/c1ob05471f. Epub 2011 Jun 3.
A wide range of N-alkylglycines (peptoids) can be efficiently prepared via Ugi reactions using microwave irradiations. The results confirm the versatility and efficiency of the methodology for the preparation of functionalized peptoids. The products can be used in consecutive Ugi reactions to yield cyclic peptoids of potential biological interest.
通过微波辐射的 Ugi 反应可以高效制备多种 N-烷基甘氨酸（肽）。这些结果证实了该方法在制备功能化肽方面的多功能性和高效性。所得产物可用于连续的 Ugi 反应，以生成具有潜在生物学意义的环状肽。
