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内镜套扎(EBL)优于内镜夹闭治疗结肠憩室出血。

Enodoscopic band ligation (EBL) is superior to endoscopic clipping for the treatment of colonic diverticular hemorrhage.

机构信息

Department of Gastroenterology, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, Japan.

出版信息

Surg Endosc. 2011 Nov;25(11):3574-8. doi: 10.1007/s00464-011-1760-8. Epub 2011 Jun 3.

DOI:10.1007/s00464-011-1760-8
PMID:21638178
Abstract

BACKGROUND

Recently, endoscopic band ligation (EBL) has been used to treat colonic diverticular hemorrhage, but the number of EBL cases treated to date has been limited. This study aimed to evaluate the clinical outcomes of EBL in the treatment of colonic diverticular hemorrhage compared with those of endoclips.

METHODS

At St. Luke's International Hospital in Tokyo, 66 patients were treated with EBL or endoclips from January 2004 to October 2010. Early rebleeding was defined as clinical evidence of recurrent bleeding within 30 days after initial treatment. Patients' demographics, rate of early rebleeding, and complications were retrospectively evaluated.

RESULTS

Of the 66 patients, 18 were treated with EBL. The initial success rate for hemostasis with EBL was 100% with no complications. Early rebleeding was observed in one patient (6%), for whom eversion of a bleeding diverticulum in the sigmoid colon could not be obtained and early loss of the O-band occurred. However, the patient could be retreated with EBL. On the other hand, complete eversion could be obtained for all 10 patients with right-sided diverticula, and no early rebleeding occurred. Endoclips were used to treat 48 patients. Although the initial success rate for hemostasis was 100% without any complications, the rate of early rebleeding was 33% (16 patients), which was significantly higher than the rate for the EBL-treated group (P = 0.018).

CONCLUSIONS

According to the findings, EBL should be considered safe, effective, and superior to endoclips for the treatment of colonic diverticular hemorrhage. The EBL procedure should be attempted as the initial therapy especially for the right-sided disease.

摘要

背景

最近,内镜套扎(EBL)已被用于治疗结肠憩室出血,但迄今为止接受 EBL 治疗的病例数量有限。本研究旨在评估 EBL 治疗结肠憩室出血的临床效果,并与内镜夹治疗的效果进行比较。

方法

在东京的 St. Luke's 国际医院,2004 年 1 月至 2010 年 10 月期间,66 例患者接受了 EBL 或内镜夹治疗。早期再出血定义为初次治疗后 30 天内临床再次出血的证据。回顾性评估患者的人口统计学特征、早期再出血率和并发症。

结果

66 例患者中,18 例接受 EBL 治疗。EBL 止血的初始成功率为 100%,无并发症。1 例(6%)患者出现早期再出血,原因是乙状结肠出血憩室翻转失败且 O 型带早期丢失。但该患者可再次接受 EBL 治疗。另一方面,所有 10 例右侧憩室患者均能完全翻转,无早期再出血发生。48 例患者接受内镜夹治疗。虽然止血的初始成功率为 100%,无任何并发症,但早期再出血率为 33%(16 例),明显高于 EBL 治疗组(P=0.018)。

结论

根据这些发现,EBL 治疗结肠憩室出血安全、有效,优于内镜夹治疗。EBL 治疗应作为首选治疗方法,尤其是针对右侧病变。

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