Huang Zihan, Feng Xiaomeng, Yin Xin, Sun Tao, Fan Chongxi, Chen Hongyu, Li Bairong, Ning Shoubin
Department of Gastroenterology, Air Force Medical Center, Air Force Medical University, Beijing, China.
PeerJ. 2025 Aug 29;13:e19910. doi: 10.7717/peerj.19910. eCollection 2025.
Colonic diverticular bleeding is one of the primary causes of lower gastrointestinal bleeding, with endoscopic hemostasis as the first-line treatment. However, the outcomes of endoscopic treatments remain suboptimal. This study utilized an innovative therapeutic method to manage colonic diverticular bleeding and evaluated its feasibility and safety in clinical settings.
Between July 2018 and July 2023, 35 patients with colonic divercular bleeding were treated through argon plasma coagulation combined with endoclips (APC-EC) at the Air Force Medical Center. The technical success rate, rebleeding rate, and complications associated with the therapeutic method over a 5-year period were retrospectively analyzed.
The technical success rate of the method was 100%, the early rebleeding rate of APC-EC was 8.57%. The incidence of late rebleeding at 1-year follow-up was 5.71%, it was 0% at the 2- and 3-year follow-up periods. Intraoperative perforation was observed only in two patients treated with APC-EC; however, delayed perforation was not observed in any patient, and none of them required surgical treatment.
APC-EC might be a viable, safe, and effective method for treating colonic divercular bleeding.
结肠憩室出血是下消化道出血的主要原因之一，内镜止血是一线治疗方法。然而，内镜治疗的效果仍不尽人意。本研究采用一种创新的治疗方法来处理结肠憩室出血，并评估其在临床环境中的可行性和安全性。
2018年7月至2023年7月期间，35例结肠憩室出血患者在空军医疗中心接受了氩等离子体凝固联合内镜夹（APC-EC）治疗。回顾性分析了该治疗方法在5年期间的技术成功率、再出血率和并发症。
该方法的技术成功率为100%，APC-EC的早期再出血率为8.57%。1年随访时晚期再出血发生率为5.71%，2年和3年随访期为0%。仅在2例接受APC-EC治疗的患者中观察到术中穿孔；然而，未观察到任何患者出现延迟穿孔，且无一例需要手术治疗。
APC-EC可能是一种治疗结肠憩室出血的可行、安全且有效的方法。
