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儿科制剂给药装置:当前实践、挑战和最新进展概述。

Delivery devices for the administration of paediatric formulations: overview of current practice, challenges and recent developments.

机构信息

Pharmaceutical Development, AstraZeneca, Bakewell Road, Loughborough, Leicestershire, LE11 5RH, United Kingdom.

出版信息

Int J Pharm. 2011 Aug 30;415(1-2):221-31. doi: 10.1016/j.ijpharm.2011.05.048. Epub 2011 May 27.

DOI:10.1016/j.ijpharm.2011.05.048
PMID:21640807
Abstract

The European Paediatric Formulation Initiative (EuPFI), a group consisting of paediatric formulation experts from industry, academia and clinical pharmacy was founded with the aim of raising awareness of paediatric formulation issues. It is imperative that paediatric medicines can be administered accurately to ensure the correct dose is provided and that the administration device is easy to use and acceptable from the patient's and carer's perspectives. This reflection paper provides an overview of currently available paediatric administration devices and highlights some of the challenges associated with, recommendations and recent developments in delivery devices for the oral, inhaled, parenteral, nasal and ocular administration of paediatric formulations, on behalf of the EuPFI.

摘要

欧洲儿科制剂倡议(EuPFI)是一个由行业、学术界和临床药学领域的儿科制剂专家组成的组织,其成立目的是提高对儿科制剂问题的认识。至关重要的是,儿科药物能够准确给药,以确保提供正确的剂量,并且给药装置易于使用并从患者和护理人员的角度可以接受。本反思论文概述了目前可用的儿科给药装置,并代表 EuPFI 强调了与儿科制剂的口服、吸入、肠胃外、鼻内和眼部给药相关的一些挑战、建议和最新进展。

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