Department of Cancer Biology, Vanderbilt University, Nashville, TN, USA.
Curr Biol. 2011 Jun 7;21(11):R430-2. doi: 10.1016/j.cub.2011.04.043.
Cadherins and catenins evidently partnered at the dawn of the animal kingdom to enable the first polarized epithelium, and perhaps animal evolution itself. New evidence from a primitive slime mold, however, suggests that α- and β-catenins may have engaged this function independently, long before cadherins arrived on the scene.
钙黏蛋白和连环蛋白显然在动物王国的黎明时分就合作形成了第一个极化上皮细胞，并可能促成了动物进化本身。然而，来自原始黏菌的新证据表明，α-连环蛋白和β-连环蛋白可能在钙黏蛋白出现之前很久就已经独立地参与了这一功能。
