Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK.
Vet J. 2012 Mar;191(3):396-8. doi: 10.1016/j.tvjl.2011.04.018.
The effects of essential fatty acid supplementation (EFA) on the control of idiopathic epilepsy in dogs were investigated in a blinded, placebo-controlled trial. Fifteen dogs were treated with triple purified Ω-3 oil containing 400 mg eicosapentaenoic acid, 250 mg docosahexaenoic acid and 22 mg vitamin E per 1.5 mL at a dose of 1.5 mL/10 kg once daily for 12 weeks, followed by a 12 week placebo period of supplementation with olive oil. Owners recorded seizure frequency and severity and any adverse events. EFA supplementation did not reduce seizure frequency or severity in dogs with idiopathic epilepsy.
一项双盲、安慰剂对照试验研究了必需脂肪酸（EFA）补充对控制犬特发性癫痫的影响。15 只犬接受了三重纯化的 Ω-3 油治疗，每 1.5 毫升含有 400 毫克二十碳五烯酸、250 毫克二十二碳六烯酸和 22 毫克维生素 E，剂量为 1.5 毫升/10 公斤，每天一次，持续 12 周，随后用橄榄油进行 12 周的安慰剂补充。主人记录了癫痫发作的频率和严重程度以及任何不良反应。EFA 补充并没有降低特发性癫痫犬的癫痫发作频率或严重程度。
