Horton J C, Dagi L R, McCrane E P, de Monasterio F M
Center for Sight, Georgetown University Medical Center, Washington, DC.
Arch Ophthalmol. 1990 Jul;108(7):1025-31. doi: 10.1001/archopht.1990.01070090127054.
The arrangement of the ocular dominance columns in the human primary visual cortex was studied by examining cytochrome oxidase activity in autopsy specimens of occipital lobes obtained from two patients who became blind in one eye before death. By artificially flattening the cortex before processing, it was possible to reconstruct the pattern formed by the ocular dominance columns throughout most of the primary visual cortex. The columns form a mosaic of irregular parallel stripes about 500 microns to 1000 microns wide (right eye column plus left eye column measures 1 to 2 mm), oriented at right angles to the boundary of the primary visual cortex. The columns are wider near the boundary of the primary visual cortex and within the representation of the peripheral visual field, the ocular dominance columns of the ipsilateral eye become fragmented until they disappear altogether at the border of the monocular crescent representation. The arrangement of ocular dominance columns in the human visual cortex is very similar to the pattern reported in the macaque monkey, although the columns in humans are wider.
通过检测从两名生前单眼失明患者的枕叶尸检标本中细胞色素氧化酶的活性，研究了人类初级视觉皮层中眼优势柱的排列情况。在处理标本前通过人工展平皮层，得以重建大部分初级视觉皮层中眼优势柱形成的模式。这些柱形成了不规则平行条纹的镶嵌图案，宽约500微米至1000微米（右眼柱加左眼柱的宽度为1至2毫米），与初级视觉皮层的边界成直角排列。这些柱在初级视觉皮层边界附近以及周边视野的表征范围内更宽，同侧眼的眼优势柱会逐渐碎片化，直至在单眼半月形表征的边界处完全消失。人类视觉皮层中眼优势柱的排列与猕猴中报道的模式非常相似，尽管人类的柱更宽。
