Department of Community and Family Medicine, Duke University Medical Center and Duke Global Health Institute, Durham, NC, USA.
Matern Child Health J. 2012 Jul;16(5):1015-20. doi: 10.1007/s10995-011-0828-3.
Early life physical activity may help prevent obesity but is difficult to measure. The purpose of this study was to examine associations of age of achievement of gross motor milestones in infancy with adiposity at age 3 years. Seven forty one mother/infant dyads participated in a longitudinal study in Massachusetts. Exposures were age of attainment of 4 gross motor milestones-rolling over, sitting up, crawling, and walking. Outcomes were 3-year sum of subscapular and triceps skinfold thickness (SS + TR) for overall adiposity, their ratio (SS:TR) for central adiposity, and body mass index (BMI) z-score. We used linear regression models adjusted for confounders to examine motor milestone achievement and later adiposity. Rolling over (0.04, 95% CI: 0.008, 0.07) and sitting up (0.02, 95% CI: 0.001, 0.05) at ≥ 6 months were associated with increased SS:TR compared with attainment before 6 months. Walking at ≥ 15 months was associated with 0.98 mm higher SS + TR (95% CI: 0.05, 1.91) compared with walking before 12 months. Age at crawling was not associated with the outcomes. None of the milestones were associated with BMI z-score. Age of motor milestone achievement was only a modest predictor of adiposity. Later rolling over and sitting up were associated with greater central adiposity, and later age at walking was associated with greater overall adiposity at age 3 years. Although we controlled for birth weight and 6-month weight-for-length in our models, more detailed assessment of early adiposity prior to achievement of motor milestones is needed to help determine causality.
早期的身体活动可能有助于预防肥胖,但很难衡量。本研究的目的是探讨婴儿期大运动里程碑达成年龄与 3 岁时肥胖的关系。741 对母婴对参加了马萨诸塞州的一项纵向研究。暴露因素是婴儿期 4 项大运动里程碑(翻身、坐起、爬行和行走)的达成年龄。结果是 3 岁时肩胛下和肱三头肌皮褶厚度总和(SS + TR)作为总体肥胖的指标,其比值(SS:TR)作为中心肥胖的指标,以及体重指数(BMI)z 评分。我们使用线性回归模型调整混杂因素来检验运动里程碑的达成与之后的肥胖情况。与 6 个月前达成相比,6 个月或以上达成翻身和坐起与 SS:TR 增加有关(分别为 0.04,95%CI:0.008,0.07 和 0.02,95%CI:0.001,0.05)。与 12 个月前相比,15 个月或以上达成行走与 SS + TR 增加 0.98mm(95%CI:0.05,1.91)有关。爬行年龄与结果无关。没有一个里程碑与 BMI z 评分有关。运动里程碑的达成年龄只是肥胖的一个适度预测因素。较晚的翻身和坐起与更大的中心肥胖有关,而较晚的行走年龄与 3 岁时的总体肥胖有关。虽然我们在模型中控制了出生体重和 6 个月时的体重-身长比,但需要更详细地评估在达成运动里程碑之前的早期肥胖情况,以帮助确定因果关系。