Department of Medical Social Sciences, Feinberg School of Medicine at Northwestern University, 710 North Lake Shore drive, #729, Chicago, IL 60611, USA.
Qual Life Res. 2012 Mar;21(2):195-207. doi: 10.1007/s11136-011-9935-2. Epub 2011 Jun 4.
Considerable research has demonstrated the negative psychosocial impact of cancer. Recent work has highlighted positive psychosocial outcomes. Research is now needed to evaluate the relationship between negative and positive impacts. This paper reports the development and validation of a measurement model capturing positive and negative psychosocial illness impacts.
The sample included 754 cancer patients on- or post-treatment. Item development was informed by literature review, expert input patient interviews and the results of a pilot study of 205 cancer patients, resulting in 43 positive and 46 negative items. Factor analyses were used to evaluate the dimensionality of the item pools. Analysis of variance (ANOVA) was used to examine relationships between psychosocial illness impact and other variables.
Unidimensionality was demonstrated within but not across negative and positive impact items. ANOVA results showed differential relationships between negative and positive impacts, respectively, and patient sociodemographic and clinical variables.
Positive and negative psychosocial illness impacts are best conceptualized and measured as two independent factors. Computerized adaptive tests and short-form measures developed from this comprehensive psychosocial illness impact item bank may benefit future research and clinical applications.
大量研究表明癌症会产生负面的心理社会影响。最近的研究强调了积极的心理社会结果。现在需要研究来评估负面和正面影响之间的关系。本文报告了一种测量模型的开发和验证，该模型可以捕捉积极和消极的心理社会疾病影响。
该样本包括 754 名正在接受或已完成治疗的癌症患者。通过文献回顾、专家意见、患者访谈以及对 205 名癌症患者的初步研究结果，得出了 43 个积极和 46 个消极项目，为项目的发展提供了信息。使用因子分析来评估项目池的维度。方差分析（ANOVA）用于检验心理社会疾病影响与其他变量之间的关系。
在负向和正向影响项目内证明了单维性，但在项目间没有证明。方差分析结果表明，负向和正向影响分别与患者的社会人口统计学和临床变量之间存在差异关系。
积极和消极的心理社会疾病影响最好被概念化为两个独立的因素。从这个全面的心理社会疾病影响项目库中开发的计算机化自适应测试和简短形式的测量工具可能会有益于未来的研究和临床应用。
