鳗鱼的胰腺含有类阿片物质，但不含促肾上腺皮质激素样物质。

The eel pancreas contains opiate-like but not corticotropin-like materials.

作者信息

Ng T B

机构信息

Department of Biochemistry, Faculty of Medicine, Chinese University, Hong Kong, Shatin, N.T.

出版信息

Biochem Int. 1990;20(6):1161-7.

PMID:2164398

Abstract

Eel pancreatic acetone powder was extracted with an acetone-water-HCL mixture. An acid acetone powder was formed by addition of a copious volume of cold acetone to the extract. The powder was subsequently subjected to gel filtration on Sephadex G25. Opiate receptor binding activity was present mainly in fractions retarded on Sephadex G25 (MW less than 5,000) although some activity was present in the unretarded fraction (MW greater than 5,000). Steroidogenic activity was absent from all fractions.

摘要

用丙酮 - 水 - 盐酸混合物提取鳗鱼胰腺丙酮粉。向提取物中加入大量冷丙酮形成酸性丙酮粉。随后将该粉末在葡聚糖凝胶G25上进行凝胶过滤。阿片受体结合活性主要存在于在葡聚糖凝胶G25上滞留的级分中（分子量小于5000），尽管在未滞留级分中（分子量大于5000）也存在一些活性。所有级分均无类固醇生成活性。