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第十五届国际肝脏窦状隙细胞研讨会,2010 年。

15th International Symposium on Cells of the Hepatic Sinusoid, 2010.

机构信息

Division of Gastrointestinal and Liver Diseases, University of Southern California Keck School of Medicine, Los Angeles, CA 90069, USA.

出版信息

Liver Int. 2011 Jul;31(6):762-72. doi: 10.1111/j.1478-3231.2011.02527.x. Epub 2011 Apr 19.

DOI:10.1111/j.1478-3231.2011.02527.x
PMID:21645207
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4388239/
Abstract

This is a meeting report of the presentations given at the 15th International Symposium on Cells of the Hepatic Sinusoid, held in 2010. The areas covered include the contributions of the various liver cell populations to liver disease, molecular and cellular targets involved in steatohepatitis, hepatic fibrosis and cancer and regenerative medicine. In addition to a review of the science presented at the meeting, this report provides references to recent literature on the topics covered at the meeting.

摘要

这是 2010 年第 15 届肝窦细胞国际研讨会报告的会议记录。涵盖的领域包括各种肝实质细胞群对肝脏疾病的贡献、脂肪性肝炎、肝纤维化和癌症以及再生医学相关的分子和细胞靶点。除了对会议上提出的科学内容进行综述外,本报告还提供了有关会议涉及主题的最新文献的参考文献。

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Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice.Toll 样受体 4 通过小鼠骨髓来源的和内源性的肝细胞介导酒精性脂肪性肝炎。
Alcohol Clin Exp Res. 2011 Aug;35(8):1509-18. doi: 10.1111/j.1530-0277.2011.01487.x. Epub 2011 Apr 4.
2
Septum transversum-derived mesothelium gives rise to hepatic stellate cells and perivascular mesenchymal cells in developing mouse liver.中膈衍生的间皮细胞在发育中的小鼠肝脏中产生肝星状细胞和血管周间质细胞。
Hepatology. 2011 Mar;53(3):983-95. doi: 10.1002/hep.24119. Epub 2011 Feb 3.
3
Molecular mechanisms of alcoholic liver disease: innate immunity and cytokines.酒精性肝病的分子机制:固有免疫与细胞因子。
Alcohol Clin Exp Res. 2011 May;35(5):787-93. doi: 10.1111/j.1530-0277.2010.01399.x. Epub 2011 Feb 1.
4
Defects in hepatic Notch signaling result in disruption of the communicating intrahepatic bile duct network in mice.肝脏 Notch 信号通路缺陷导致小鼠肝内胆管网络的连通性中断。
Dis Model Mech. 2011 May;4(3):359-67. doi: 10.1242/dmm.005793. Epub 2011 Jan 31.
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Lineage restriction of human hepatic stem cells to mature fates is made efficient by tissue-specific biomatrix scaffolds.组织特异性生物基质支架可提高人肝干细胞向成熟命运分化的效率。
Hepatology. 2011 Jan;53(1):293-305. doi: 10.1002/hep.24012. Epub 2010 Dec 13.
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Mammalian target of rapamycin mediates the angiogenic effects of leptin in human hepatic stellate cells.哺乳动物雷帕霉素靶蛋白介导瘦素对人肝星状细胞的促血管生成作用。
Am J Physiol Gastrointest Liver Physiol. 2011 Aug;301(2):G210-9. doi: 10.1152/ajpgi.00047.2010. Epub 2011 Jan 20.
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CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice.CD1d 限制性自然杀伤 T 细胞促进小鼠肝脏炎症和纤维化。
J Hepatol. 2011 Jun;54(6):1195-204. doi: 10.1016/j.jhep.2010.08.022. Epub 2010 Nov 5.
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Vascular endothelial growth factor receptor-1 signaling promotes liver repair through restoration of liver microvasculature after acetaminophen hepatotoxicity.血管内皮生长因子受体-1 信号通路通过修复乙酰氨基酚肝毒性后的肝微血管促进肝脏修复。
Toxicol Sci. 2011 Mar;120(1):218-29. doi: 10.1093/toxsci/kfq366. Epub 2010 Dec 6.
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Alcohol induces RNA polymerase III-dependent transcription through c-Jun by co-regulating TATA-binding protein (TBP) and Brf1 expression.酒精通过共调控 TATA 结合蛋白 (TBP) 和 Brf1 表达,通过 c-Jun 诱导 RNA 聚合酶 III 依赖性转录。
J Biol Chem. 2011 Jan 28;286(4):2393-401. doi: 10.1074/jbc.M110.192955. Epub 2010 Nov 24.
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