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兔出血性致死疾病病原体杯状病毒的纯化与特性分析

Purification and characterization of a calicivirus as the causative agent of a lethal hemorrhagic disease in rabbits.

作者信息

Parra F, Prieto M

机构信息

Departamento de Biología Funcional (Area de Bioquímica), Facultad de Medicina, Universidad de Oviedo, Spain.

出版信息

J Virol. 1990 Aug;64(8):4013-5. doi: 10.1128/JVI.64.8.4013-4015.1990.

DOI:10.1128/JVI.64.8.4013-4015.1990
PMID:2164609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC249702/
Abstract

The causative viral agent of a lethal rabbit hemorrhagic disease has been purified and characterized. In negative-stained preparations, the virions were icosahedral, measured 27 to 35 nm in diameter, were without an envelope, and showed 10 peripheral cup-shaped depressions. The major structural protein was 60 kilodaltons, which constitutes a unique characteristic of the Caliciviridae.

摘要

一种致死性兔出血性疾病的致病病毒病原体已被纯化并进行了特性鉴定。在负染制剂中，病毒粒子呈二十面体，直径为27至35纳米，无包膜，并呈现出10个周边杯状凹陷。主要结构蛋白为60千道尔顿，这是杯状病毒科的一个独特特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d3/249702/ec8ff645cf2a/jvirol00063-0462-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d3/249702/17297f3cc826/jvirol00063-0462-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d3/249702/935ec2b6596a/jvirol00063-0462-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d3/249702/ec8ff645cf2a/jvirol00063-0462-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d3/249702/17297f3cc826/jvirol00063-0462-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d3/249702/935ec2b6596a/jvirol00063-0462-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d3/249702/ec8ff645cf2a/jvirol00063-0462-c.jpg

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