Department of Pediatric Infectious Diseases, Johns Hopkins Medical Institution, 200 N Wolfe St, Suite 3150, Baltimore, MD 21287, USA.
Pediatrics. 2011 Jul;128(1):e242-5. doi: 10.1542/peds.2010-3504. Epub 2011 Jun 6.
Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis represents a new category of immune-mediated neurologic disorders. Viral encephalitis is often the presumptive diagnosis because of the acute neurologic changes, cerebrospinal fluid lymphocytic pleocytosis, and occasional hyperthermia. We report here the case of a previously healthy 7-year-old boy with new-onset aggressive behavior, seizure activity, and orofacial dyskinesias with cerebrospinal fluid and serum that tested positive for anti-NMDA receptors.
抗 N-甲基-D-天冬氨酸 (NMDA) 受体脑炎是一种新型免疫介导的神经疾病。由于急性神经改变、脑脊液淋巴细胞增多和偶尔发热，病毒性脑炎常被初步诊断。我们在此报告一例先前健康的 7 岁男孩，新出现攻击性行为、癫痫发作和口面部运动障碍，脑脊液和血清 NMDA 受体检测阳性。
