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[辐射防护剂对受辐照动物小肠黏膜上皮的影响]

[Effect of radioprotective agents on the epithelium of small intestine mucosa in irradiated animals].

作者信息

Grigor'eva E V, Pozharisskaia T D, Chigareva N G

出版信息

Radiobiologiia. 1986 May-Jun;26(3):410-3.

PMID:3737892
Abstract

In experiments on irradiated (10 Gy) mice a study was made of the morphological changes in the small intestine mucosa and in its functional status estimated by absorption of stain uranine. It was shown that the preventive administration of cystamine and S-(omega)-aminopropyl-beta-aminoethylthiophosphoric acid to the exposed mice increased the proliferation processes in the crypt and the cell movement per villus providing a favourable effect of the radioprotective agents on the absorption function.

摘要

在对受辐照(10戈瑞)小鼠进行的实验中,研究了小肠黏膜的形态变化及其通过吸收荧光素钠评估的功能状态。结果表明,对受辐照小鼠预防性给予胱胺和S-(ω)-氨丙基-β-氨乙基硫代磷酸,可增加隐窝中的增殖过程以及每个绒毛的细胞移动,从而使辐射防护剂对吸收功能产生有利影响。

相似文献

1
[Effect of radioprotective agents on the epithelium of small intestine mucosa in irradiated animals].[辐射防护剂对受辐照动物小肠黏膜上皮的影响]
Radiobiologiia. 1986 May-Jun;26(3):410-3.
2
[Radioprotective effect of drug combinations on the small intestine].药物组合对小肠的辐射防护作用
Radiobiologiia. 1986 May-Jun;26(3):402-4.
3
[Simulation of cell renewal in the small intestine epithelium of intact and irradiated animals].[完整动物和受辐照动物小肠上皮细胞更新的模拟]
Dokl Akad Nauk SSSR. 1987;294(3):712-5.
4
Intestinal crypt survival and total and per crypt levels of proliferative cellularity following irradiation: single x-ray exposures.照射后肠道隐窝存活率以及增殖细胞的总量和每个隐窝的水平:单次X射线照射。
Radiat Res. 1971 Jun;46(3):533-46.
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Radiobiologiia. 1990 May-Jun;30(3):348-52.
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[Morphological characteristics of the radiation lesion of the small intestine mucosa in irradiated mice treated with homologous bone marrow administration].[给予同源骨髓的受照射小鼠小肠黏膜辐射损伤的形态学特征]
Radiobiologiia. 1981 Nov-Dec;21(6):929-32.
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Melatonin and roentgen irradiation-induced acute radiation enteritis in Albino rats: an animal model.褪黑素与X线照射诱导的白化大鼠急性放射性肠炎:一种动物模型
Cell Biol Int. 2008 Nov;32(11):1353-61. doi: 10.1016/j.cellbi.2008.08.001. Epub 2008 Aug 13.
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[Radioprotective effects of natural beta-carotene on villi and crypts in abdominally radiated mice].天然β-胡萝卜素对腹部受辐射小鼠绒毛和隐窝的辐射防护作用
Nihon Igaku Hoshasen Gakkai Zasshi. 2002 Dec;62(14):822-31.
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[Relation between the toxic killing of mouse small intestine enterocytes and the interval between the administration of the S-specific agent hydroxyurea].[S特异性药物羟基脲给药间隔与小鼠小肠肠上皮细胞毒性杀伤之间的关系]
Biull Eksp Biol Med. 1986 Jun;101(6):746-9.
10
[Number of cells in the small intestinal mucosa of irradiated mice as an index of the degree of protection of this organ by radioprotectors].
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