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[辐射防护剂对受辐照动物小肠黏膜上皮的影响]

[Effect of radioprotective agents on the epithelium of small intestine mucosa in irradiated animals].

作者信息

Grigor'eva E V, Pozharisskaia T D, Chigareva N G

出版信息

Radiobiologiia. 1986 May-Jun;26(3):410-3.

PMID:3737892
Abstract

In experiments on irradiated (10 Gy) mice a study was made of the morphological changes in the small intestine mucosa and in its functional status estimated by absorption of stain uranine. It was shown that the preventive administration of cystamine and S-(omega)-aminopropyl-beta-aminoethylthiophosphoric acid to the exposed mice increased the proliferation processes in the crypt and the cell movement per villus providing a favourable effect of the radioprotective agents on the absorption function.

摘要

在对受辐照(10戈瑞)小鼠进行的实验中,研究了小肠黏膜的形态变化及其通过吸收荧光素钠评估的功能状态。结果表明,对受辐照小鼠预防性给予胱胺和S-(ω)-氨丙基-β-氨乙基硫代磷酸,可增加隐窝中的增殖过程以及每个绒毛的细胞移动,从而使辐射防护剂对吸收功能产生有利影响。

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