Vladimirov V G, Konovalova L I, Tarnopol'skaia L G
Radiobiologiia. 1986 May-Jun;26(3):402-4.
The study of the radioprotective effect of complexes containing small amounts of cystamine or gammaphos mixed with mexamine, gutimine and ethyrone on mouse small intestine showed high efficiency of the drugs as determined by cellularity and DNA-synthesizing activity of intestinal epithelium. This is connected with the influence of the complex mexamine + gutimine + ethyrone on the pharmacodynamics and pharmacokinetics of cystamine and gammaphos.
对含有少量胱胺或γ-磷与美沙明、古替明和乙色酮混合的复合物对小鼠小肠辐射防护作用的研究表明,根据肠上皮细胞数量和DNA合成活性测定,这些药物具有高效性。这与美沙明+古替明+乙色酮复合物对胱胺和γ-磷的药效学和药代动力学的影响有关。