Division of Gastroenterology, University of California, Irvine, Orange, CA, USA.
Dig Dis Sci. 2011 Dec;56(12):3602-9. doi: 10.1007/s10620-011-1766-z. Epub 2011 Jun 7.
Mental and physical health-related quality of life (HRQOL) are important health impact measures following military deployment. While conditions such as post-traumatic stress disorder (PTSD) are known to adversely affect QOL, little is known about the effect of post-infectious functional gastrointestinal disorders (PI-FGID). Our aim was to evaluate the risk of PI-FGID and its impact on HRQOL among military personnel returning from deployment.
A cross-sectional cohort of active-duty military deployed to Egypt or Turkey between 2004 and 2005 was asked to complete a questionnaire (Rome II and SF-36 instruments) on travelers' diarrhea (TD) during deployment and FGID symptoms and HRQOL 6 months after returning from deployment.
A total of 121 military personnel returning from Egypt (n = 33) and Turkey (n = 88) completed the post-deployment questionnaire. Nearly half (48.3%) met the definition for an FGID at the time of the survey, and 53% of individuals reporting one or more episodes of TD during deployment developed an FGID, compared to 33% of those not reporting TD (odds ratio [OR] 2.2, P = 0.08). Compared to those not meeting the FGID criteria, those with post-deployment FGID had lower mean mental HRQOL scores (-13.4%, P < 0.0001) and lower physical HRQOL scores (-7.2%, P = 0.004).
There was a high prevalence of FGID symptoms in military personnel returning from deployment, and TD was a noted risk factor. FGID and symptoms decreased QOL, with mental HRQOL being affected more than physical HRQOL. These findings require further research in order to assess the long-term impact of these and other post-infectious sequela related to TD during deployments among returning veterans.
精神和身体健康相关的生活质量（HRQOL）是军事部署后重要的健康影响指标。虽然已知创伤后应激障碍（PTSD）等疾病会对 QOL 产生不利影响，但对于感染后功能性胃肠道疾病（PI-FGID）的影响知之甚少。我们的目的是评估军事部署人员中 PI-FGID 的发病风险及其对 HRQOL 的影响。
我们对 2004 年至 2005 年期间部署到埃及或土耳其的现役军人进行了一项横断面队列研究，要求他们在部署期间填写旅行者腹泻（TD）问卷（Rome II 和 SF-36 工具），并在部署后 6 个月填写 FGID 症状和 HRQOL 问卷。
共有 121 名从埃及（n = 33）和土耳其（n = 88）返回的军人完成了部署后的问卷。近一半（48.3%）在调查时符合 FGID 定义，与未报告 TD 的人相比，报告在部署期间发生过一次或多次 TD 的人中，有 53%（比值比 [OR] 2.2，P = 0.08）发生了 FGID。与未达到 FGID 标准的人相比，有 FGID 的人心理 HRQOL 评分较低（-13.4%，P < 0.0001），身体 HRQOL 评分较低（-7.2%，P = 0.004）。
从部署中返回的军人 FGID 症状的患病率较高，TD 是一个明显的危险因素。FGID 和症状降低了生活质量，心理 HRQOL 受影响大于身体 HRQOL。这些发现需要进一步研究，以评估这些发现以及其他与 TD 相关的感染后后遗症在返回的退伍军人中对生活质量的长期影响。
