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[使用标记单克隆抗体对卵巢癌和结肠癌进行免疫闪烁显像]

[Immunoscintigraphy of cancer of the ovaries and colon using labeled monoclonal antibodies].

作者信息

Gabuniia R I, Shiriaev S V, Bogdasarov Iu B, Zhordaniia K I, Anan'ev V S

出版信息

Med Radiol (Mosk). 1989 Aug;34(8):56-61.

PMID:2770446
Abstract

Immunoscintigraphy with labeled monoclonal antibodies for investigation of patients with ovarian and colon adenocarcinoma is a highly informative method which can be used for immunovisualization of primary tumor foci, their recurrences and metastases. A possibility to estimate specific tumor tissue activity was shown to be the advantage of immunoscintigraphy as compared to other special topical methods of investigation. High blood concentrations of tumor antigens did not deteriorate significantly the quality of visualization of tumor foci using labeled monoclonal antibodies.

摘要

用标记单克隆抗体进行免疫闪烁扫描以研究卵巢癌和结肠癌患者是一种信息量丰富的方法,可用于对原发性肿瘤病灶、其复发和转移灶进行免疫显像。与其他特殊的局部检查方法相比,免疫闪烁扫描的优势在于有可能估计肿瘤组织的特异性活性。使用标记单克隆抗体时,高浓度的肿瘤抗原在血液中并不会显著降低肿瘤病灶的显像质量。

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1
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Med Radiol (Mosk). 1989 Aug;34(8):56-61.
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