Maslova L N, Chernigovskaia E V, Belen'kiĭ M A, Danilova O A, Naumenko E V, Polenov A L
Fiziol Zh SSSR Im I M Sechenova. 1990 Mar;76(3):331-7.
The activation of the 11-hydroxycorticosteroids secretion by 5-hydroxytryptophan was confirmed in intact rats as well as in those with isolated mediobasal hypothalamus. Deafferentation of the medial basal hypothalamus did not prevent an increase of corticoliberin and vasopressin content in the external median eminence after adrenalectomy and led to an opposite response after 5-hydroxytryptophan injection in these rats. The activation of the vasopressinergic cells and increase of portal vessels' lumen occurred under the 5-hydroxytryptophan effect, particularly in rats subjected to deafferentation combined with adrenalectomy.
在完整大鼠以及中隔基底部下丘脑分离的大鼠中，均证实了5-羟色氨酸可激活11-羟皮质类固醇的分泌。中隔基底部下丘脑去传入神经后，并不妨碍肾上腺切除术后外侧正中隆起中促肾上腺皮质激素释放素和血管加压素含量的增加，而在这些大鼠注射5-羟色氨酸后则产生相反的反应。在5-羟色氨酸作用下，尤其是在去传入神经联合肾上腺切除的大鼠中，血管加压素能细胞被激活，门静脉管腔增大。
