Division of General Internal Medicine, Johns Hopkins University School of Medicine, 1830 East Monument Street, Room 8047a, Baltimore, MD 21205, USA.
Drug Alcohol Depend. 2011 Nov 1;118(2-3):375-82. doi: 10.1016/j.drugalcdep.2011.04.024. Epub 2011 Jun 11.
Prior studies on the course of alcohol use disorders have reported a "telescoping" effect with women progressing from drinking initiation to alcohol dependence faster than men. However, there is a paucity of population-based analyses that have examined progression to alcohol dependence comparing race/ethnicity subgroups, and little is known about whether the telescoping effect for women varies by race/ethnicity. We examined whether a telescoping effect is present in the general population comparing race/ethnicity subgroups and comparing men and women stratified by race.
This study uses data from Wave I of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) to compare a nationally representative sample of White, Black and Hispanic adults 18-44 years of age (n=21,106). Time to event analyses compare the risk of alcohol initiation, onset of alcohol dependence, and the transition from initial use to onset of alcohol dependence in the three race/ethnicity groups and for males and females in each race/ethnicity group.
Whites were younger than Blacks and Hispanics of the same sex at drinking onset and progressed to alcohol dependence at a faster rate than both Blacks and Hispanics. In addition, we found no evidence of a telescoping effect in women for any race/ethnicity group.
The present study illustrates differences in the course of transition from alcohol initiation to the development of dependence by race/ethnicity but not sex. Our findings highlight the need for additional study of factors resulting in race/ethnicity differences in order to inform culturally relevant prevention and intervention initiatives.
先前关于酒精使用障碍进程的研究报告称,女性从开始饮酒到发展为酒精依赖的速度比男性更快,存在“ telescoping ”效应。然而,基于人群的分析很少比较种族/民族亚组来研究进展为酒精依赖的情况,也很少有关于女性的 telescoping 效应是否因种族/民族而异的信息。我们研究了在一般人群中是否存在 telescopi ng 效应,比较了种族/民族亚组,并比较了按种族分层的男性和女性。
本研究使用来自全国酒精相关状况和流行病学调查( NESARC )第一波的数据,比较了年龄在 18-44 岁的白种人、黑人和西班牙裔成年人的全国代表性样本( n=21,106 )。事件时间分析比较了三个种族/民族群体以及每个种族/民族群体中的男性和女性的饮酒起始、酒精依赖发作和从初始使用到酒精依赖发作的风险。
在相同性别的情况下,白人比黑人及西班牙裔饮酒起始年龄更小,比黑人和西班牙裔发展为酒精依赖的速度更快。此外,我们没有发现任何种族/民族群体中女性存在 telescopi ng 效应的证据。
本研究说明了不同种族/民族在从开始饮酒到发展为依赖的过程中的差异,但性别因素没有影响。我们的研究结果强调了需要进一步研究导致种族/民族差异的因素,以便为文化相关的预防和干预措施提供信息。