North Oaks Neurology, Hammond, LA, USA.
Mult Scler. 2011 Nov;17(11):1387-9. doi: 10.1177/1352458511410344. Epub 2011 Jun 7.
Oral fingolimod (Gilenya) is a sphingosine-1-phosphate-receptor modulator that prevents the egress of lymphocytes from lymph nodes. Fingolimod reduces relapses and delays disability progression in patients with relapsing forms of multiple sclerosis (MS). We report a patient with MS who developed asystole and sustained bradycardia 21 hours after the first dose of fingolimod.
口服芬戈莫德(Gilenya)是一种鞘氨醇-1-磷酸受体调节剂,可阻止淋巴细胞从淋巴结迁出。芬戈莫德可减少复发多发性硬化症(MS)患者的复发并延缓残疾进展。我们报告了一例 MS 患者,该患者在首次服用芬戈莫德后 21 小时发生了心动过缓。