Albert Einstein College of Medicine, Department of Medicine, Infectious Disease Division, 1300 Morris Park Ave., UL-1223, Bronx, NY 10461, USA.
J Clin Microbiol. 2011 Aug;49(8):2992-5. doi: 10.1128/JCM.00704-11. Epub 2011 Jun 8.
lukF-PV was present in 36% of skin and soft tissue infection (SSTI)-derived methicillin-susceptible Staphylococcus aureus (MSSA) strains and comprised six distinct clones, which contained fewer enterotoxin genes than strains without lukF-PV. Clinical presentations and outcomes of lukF-PV(+) methicillin-resistant S. aureus (MRSA) and MSSA SSTIs were comparable. In multivariable analysis, the presence of lukF-PV remained a significant predictor for incision and drainage among MSSA strains.
lukF-PV 存在于 36%的皮肤和软组织感染(SSTI)来源的耐甲氧西林金黄色葡萄球菌(MSSA)菌株中,包含六个不同的克隆,这些克隆携带的肠毒素基因比没有 lukF-PV 的菌株少。lukF-PV(+)耐甲氧西林金黄色葡萄球菌(MRSA)和 MSSA 皮肤软组织感染的临床表现和结局相当。多变量分析显示,lukF-PV 的存在仍然是 MSSA 菌株切开引流的显著预测因素。