慢性乙型肝炎的联合治疗：当前适应证
Combination Therapy for Chronic Hepatitis B: Current Indications.
作者信息
Paul Navin, Han Steven-Huy
出版信息
Curr Hepat Rep. 2011 Jun;10(2):98-105. doi: 10.1007/s11901-011-0095-1. Epub 2011 Feb 19.
Abstract
Hepatitis B infection remains a major public health problem globally and in the United States, with significant use of healthcare resources. Several therapeutic agents active against viral and host targets are currently available for its treatment. The success of combination therapy in HIV infection, which has similarities to hepatitis B in both therapeutic targets and treatment options, stimulated studies on the efficacy and safety of various combinations of available drugs in the treatment of hepatitis B infection. In this review, we analyze the current role of combination therapy in chronic hepatitis B infection.
摘要
乙型肝炎感染在全球和美国仍然是一个重大的公共卫生问题，会大量消耗医疗资源。目前有几种针对病毒和宿主靶点的治疗药物可用于治疗。在治疗靶点和治疗选择方面与乙型肝炎有相似之处的HIV感染联合疗法取得的成功，激发了对现有药物各种组合治疗乙型肝炎感染的疗效和安全性的研究。在本综述中，我们分析了联合疗法在慢性乙型肝炎感染中的当前作用。
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