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使用频域光学相干断层扫描对急性视网膜色素上皮炎的短期临床观察

Short-term clinical observation of acute retinal pigment epitheliitis using spectral-domain optical coherence tomography.

作者信息

Kim Jee Wook, Jang Sun Young, Park Tae Kwann, Ohn Young-Hoon

机构信息

Department of Ophthalmology, Soonchunhyang University Hospital, Bucheon, Korea.

出版信息

Korean J Ophthalmol. 2011 Jun;25(3):222-4. doi: 10.3341/kjo.2011.25.3.222. Epub 2011 May 24.

DOI:10.3341/kjo.2011.25.3.222
PMID:21655052
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3102830/
Abstract

We investigated the case of a young man with blurred vision in his left eye. His visual acuity was slightly decreased, and ophthalmoscopy disclosed a gray-white lesion in the macula. He had no systemic or ocular history. On the visual field test, the threshold sensitivity was decreased in the corresponding region. Spectral domain optical coherence tomography (OCT) demonstrated a disruption in the photoreceptor inner and outer segment (IS/OS) junction and undulation of the retinal pigment epithelium (RPE) with backscattering. We re-examined the patient after two weeks and after three months without any treatment. Visual acuity and visual field results were gradually normalized, and OCT demonstrated the recovery of continuity in the photoreceptor IS/OS junction, as well as decreased RPE irregularity with minimal backscattering. We used spectral domain OCT instead of time domain OCT (OCT3) so that we could provide better image resolution of the acute retinal pigment epitheliitis (ARPE). Finally, we observed recovery of the functional and anatomical changes in the ARPE patient with a resolution of the condition within three months following the initial examination, using OCT and visual field tests.

摘要

我们调查了一名左眼视力模糊的年轻男性病例。他的视力略有下降,眼底检查发现黄斑区有灰白色病变。他没有全身或眼部病史。在视野测试中,相应区域的阈值敏感性降低。频域光学相干断层扫描(OCT)显示光感受器内、外节(IS/OS)交界处中断,视网膜色素上皮(RPE)有起伏并伴有后向散射。在未进行任何治疗的情况下,我们在两周和三个月后对患者进行了复查。视力和视野结果逐渐恢复正常,OCT显示光感受器IS/OS交界处连续性恢复,RPE不规则性降低且后向散射最小。我们使用频域OCT而非时域OCT(OCT3),以便能提供急性视网膜色素上皮炎(ARPE)更好的图像分辨率。最后,通过OCT和视野测试,我们观察到该ARPE患者在初次检查后的三个月内病情得到缓解,功能和解剖学改变均恢复。

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