Pôle de Pediatric Multidisciplinaire, Hôpital Necker, Université René Descartes, 75015 Paris, France.
J Cyst Fibros. 2011 Jun;10 Suppl 2:S16-23. doi: 10.1016/S1569-1993(11)60004-0.
Patients with cystic fibrosis (CF) are at risk of developing low bone mineral density (BMD) and fragility fractures. This paper presents consensus statements that summarise current knowledge of the epidemiology and pathophysiology of CF-related skeletal deficits and provides guidance on its assessment, prevention and treatment. The statements were validated using a modified Delphi methodology.
囊性纤维化(CF)患者有发生低骨密度(BMD)和脆性骨折的风险。本文提出了一些共识性陈述,总结了 CF 相关骨骼缺陷的流行病学和病理生理学的现有知识,并就其评估、预防和治疗提供了指导。这些陈述是使用改良 Delphi 方法验证的。