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猫抓病性神经视网膜炎的光学相干断层扫描黄斑病变。

Macular findings on optical coherence tomography in cat-scratch disease neuroretinitis.

机构信息

Department of Ophthalmology, Tel-Aviv Medical Center, Tel-Aviv, Israel.

出版信息

Eye (Lond). 2011 Aug;25(8):1064-8. doi: 10.1038/eye.2011.125. Epub 2011 Jun 10.

Abstract

PURPOSE

To describe the macular findings on optical coherence tomography (OCT) in patients with cat-scratch disease (CSD) neuroretinitis.

METHODS

Medical records of all patients diagnosed with CSD neuroretinitis at the Tel Aviv Medical Center between April 2006 and May 2010 were retrospectively reviewed. All patients underwent Stratus OCT macular examination.

RESULTS

Eight eyes of seven patients with confirmed CSD neuroretinitis, (mean age 33 ± 9.9 years, range 6-48 years) were included in the study. All patients presented clinically with optic nerve swelling and macular edema or macular exudates. OCT demonstrated flattening of the foveal contour, thickening of the neurosensory retina, and accumulation of subretinal fluid (SRF) in all studied eyes. Retinal exudates appeared as multiple hyper-reflective foci in the outer plexiform layer. The average central macular thickness was 460 μm (range 170-906 μm) and the average maximal retinal thickness was 613 μm (range 387-1103 μm), at presentation. The macula appeared normal on repeated exams during follow-up.

CONCLUSION

Similar OCT findings were demonstrated in patients with CSD neuroretinitis. SRF was found in all eyes, although was not visible on clinical examination or fluorescein angiography. OCT may be used as an adjunct imaging tool in the diagnosis and follow-up of patients with CSD neuroretinitis.

摘要

目的

描述猫抓病(CSD)性神经视网膜炎患者的光学相干断层扫描(OCT)的黄斑结果。

方法

回顾性分析 2006 年 4 月至 2010 年 5 月在特拉维夫医疗中心确诊为 CSD 性神经视网膜炎的所有患者的病历。所有患者均接受 Stratus OCT 黄斑检查。

结果

本研究纳入了 7 例确诊为 CSD 性神经视网膜炎的 8 只眼(平均年龄 33 ± 9.9 岁,范围 6-48 岁)。所有患者均表现为视神经肿胀和黄斑水肿或黄斑渗出。OCT 显示所有研究眼的黄斑中心凹轮廓变平,神经感觉层增厚,视网膜下液(SRF)积聚。视网膜渗出在外界质层呈多个高反射焦点。平均中央黄斑厚度为 460μm(范围 170-906μm),平均最大视网膜厚度为 613μm(范围 387-1103μm)。在随访过程中,黄斑在重复检查中正常。

结论

CSD 性神经视网膜炎患者的 OCT 结果相似。所有眼均发现 SRF,但在临床检查或荧光素血管造影中不可见。OCT 可作为诊断和随访 CSD 性神经视网膜炎患者的辅助成像工具。

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