El Sheikh Abdulrahman, Al Malki Ahmed, El Shiekh Mohamed A, Al Robayan Abdulrahman
Department of Gastroenterology, Military Hospital, Riyadh, Saudi Arabia.
Hepatogastroenterology. 2011 Mar-Apr;58(106):336-46.
BACKGROUND/AIMS: Patients with hydatid cysts (336) were studied at Riyadh Military Hospital, Saudi Arabia, between February 1985-June 2008, out of which 254 patients underwent non-surgical management and 82 patients had surgery.
Drug therapy was administered to 194 of 254 patients: albendazole was administered in 65 patients; (albendazole+praziquantel) in 129 patients; 12 patients had endoscopic management; 48 patients had Percutaneous-Aspiration-Injection-Reaspiration (PAIR) and 82 patients had surgery.
Out of 65 patients, 34 had completed albendazole of which 12 (35%), had cyst disappearance, 8 patients had partial cyst reduction, 12 had no response and were referred for combined therapy or PAIR; 66 patients with cysts in different organs completed the study using albendazole+praziquantel, in 50% of these cysts had disappeared and 16 (24%) observed reduction of cysts; 48 patients underwent PAIR, of which in 36 cysts (66.66%) disappeared; 82 patients had surgery and 20% had post-surgical complications.
A great advance recently has happened in the non-surgical management of hydatid cysts including medical, PAIR and endoscopic management, which has led to a significant reduction in the need for surgical intervention.
背景/目的：1985年2月至2008年6月期间，在沙特阿拉伯利雅得军事医院对336例包虫囊肿患者进行了研究，其中254例患者接受了非手术治疗，82例患者接受了手术治疗。
254例患者中的194例接受了药物治疗：65例患者使用阿苯达唑；129例患者使用（阿苯达唑+吡喹酮）；12例患者接受了内镜治疗；48例患者接受了经皮穿刺抽吸注射再抽吸（PAIR）治疗，82例患者接受了手术治疗。
65例使用阿苯达唑的患者中，34例完成了治疗，其中12例（35%）囊肿消失，8例囊肿部分缩小，12例无反应，转而接受联合治疗或PAIR治疗；66例不同器官囊肿患者完成了阿苯达唑+吡喹酮治疗，其中50%的囊肿消失，16例（24%）囊肿缩小；48例接受PAIR治疗的患者中，36例（66.66%）囊肿消失；82例接受手术治疗的患者中，20%出现了术后并发症。
近年来，包虫囊肿的非手术治疗取得了巨大进展，包括药物治疗、PAIR治疗和内镜治疗，这显著减少了手术干预的需求。
