Mohamed A E, Yasawy M I, Al Karawi M A
Department of Gastroenterology, Armed Forces Hospital, Riyadh, Saudi Arabia.
Hepatogastroenterology. 1998 Sep-Oct;45(23):1690-4.
BACKGROUND/AIMS: This study was conducted to evaluate the effect of different regimens of medical treatment in hydatid disease at the Armed Forces Hospital, Riyadh.
Between April 1985 and August 1990 albendazole was used alone in the treatment of 22 patients with hydatid disease, mainly of the liver. Since September 1990, we have used a combination treatment of albendazole and praziquantel in 19 patients.
For those patients treated only with albendazole, 8 patients (36.4%) showed a complete disappearance of the cyst, in 4 of which the treatment period ranged between 6 months to 2 years. The other 4 patients had ruptured liver cyst into biliary tree and had endoscopic treatment with complete recovery over a short period. For those patients treated with albendazole and praziquantel the following results were found. During a follow-up period of 2 months to 3 years and a treatment period of only 2-6 months there was complete disappearance of the hydatid cyst in 9 patients (47.4%) and over 50% reduction of the hydatid cyst in 5 patients (36.84%).
Combination treatment with albendazole and praziquantel for hydatid disease is more effective than albendazole alone.
背景/目的：本研究旨在评估利雅得武装部队医院不同药物治疗方案对包虫病的疗效。
1985年4月至1990年8月，单独使用阿苯达唑治疗22例主要为肝脏包虫病的患者。自1990年9月起，我们对19例患者采用阿苯达唑与吡喹酮联合治疗。
仅接受阿苯达唑治疗的患者中，8例（36.4%）囊肿完全消失，其中4例治疗期为6个月至2年。另外4例患者肝囊肿破裂进入胆管树，接受内镜治疗后短期内完全康复。接受阿苯达唑和吡喹酮联合治疗的患者有以下结果。在2个月至3年的随访期内，治疗期仅2 - 6个月，9例（47.4%）患者的包虫囊肿完全消失，5例（36.84%）患者的包虫囊肿缩小超过50%。
阿苯达唑与吡喹酮联合治疗包虫病比单独使用阿苯达唑更有效。
