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儿科患者鼻内用药的使用。

Use of intranasal medications in pediatric patients.

作者信息

Warrington Susan E, Kuhn Robert J

机构信息

University of Kentucky HealthCare, Lexington, Kentucky, USA.

出版信息

Orthopedics. 2011 Jun;34(6):456. doi: 10.3928/01477447-20110427-20.

DOI:10.3928/01477447-20110427-20
PMID:21661677
Abstract

A growing body of evidence supports the intranasal administration of atomized medications for a wide variety of pediatric indications. This article describes their use applicable to orthopedic specialists in the areas of pediatric pain management, as well as pre- and intraoperative sedation. As a quick, painless alternative to more invasive routes of administration, intranasal drug delivery has shown similar time to clinical effect compared to the intravenous route, while minimizing anxiety in both patients and their parents.

摘要

越来越多的证据支持通过鼻腔给药雾化药物用于多种儿科适应症。本文介绍了其在儿科疼痛管理以及术前和术中镇静领域对骨科专家的适用情况。作为一种比侵入性更强的给药途径更快、无痛的替代方法,鼻腔给药与静脉给药相比,临床起效时间相似,同时将患者及其家长的焦虑降至最低。

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1
Use of intranasal medications in pediatric patients.儿科患者鼻内用药的使用。
Orthopedics. 2011 Jun;34(6):456. doi: 10.3928/01477447-20110427-20.
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Intranasal medications in pediatric emergency medicine.儿科急诊医学中的鼻内用药
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Intranasal medication delivery for children: a brief review and update.鼻腔内给药剂型用于儿童:简要综述和更新。
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Safe and sound: pediatric procedural sedation and analgesia.安然无恙:儿科程序性镇静与镇痛
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Postoperative sedation and analgesia after pediatric liver transplantation.
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Factors associated with administration route when using midazolam for pediatric conscious sedation.使用咪达唑仑进行小儿清醒镇静时与给药途径相关的因素。
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A comparative clinical study of injection clonidine versus midazolam in supraclavicular brachial plexus block for sedation and postoperative analgesia.可乐定注射液与咪达唑仑用于锁骨上臂丛神经阻滞镇静及术后镇痛的比较临床研究
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The safety and efficacy of intranasal midazolam sedation combined with inhalation sedation with nitrous oxide and oxygen in paediatric dental patients as an alternative to general anaesthesia.鼻内咪达唑仑镇静联合一氧化二氮与氧气吸入镇静在儿科牙科患者中作为全身麻醉替代方法的安全性和有效性。
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What is meant by a "safe and effective sedation technique"?“安全有效的镇静技术”是什么意思?
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引用本文的文献

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Randomized Clinical Trial to Evaluate the Efficacy and Tolerability of Nebulized Hyaluronic Acid and Xylitol Based Solution after Septoturbinoplasty.评估鼻中隔鼻甲成形术后雾化吸入透明质酸和木糖醇溶液的疗效及耐受性的随机临床试验
J Pers Med. 2023 Jul 20;13(7):1160. doi: 10.3390/jpm13071160.
2
A cohort study of intranasal fentanyl for procedural pain management in neonates.一项关于鼻内芬太尼用于新生儿程序性疼痛管理的队列研究。
Paediatr Child Health. 2018 Dec;23(8):e170-e175. doi: 10.1093/pch/pxy060. Epub 2018 May 24.
3
Effect of Intranasal Sedation Using Ketamine and Midazolam on Behavior of 3-6 Year-Old Uncooperative Children in Dental Office: A Clinical Trial.
氯胺酮与咪达唑仑鼻内镇静对牙科诊室3 - 6岁不合作儿童行为的影响:一项临床试验
J Dent (Tehran). 2017 Jan;14(1):1-6.
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Efficacy of Intranasal Dexmedetomidine for Conscious Sedation in Patients Undergoing Surgical Removal of Impacted Third Molar: A Double-Blind Split Mouth Study.鼻内注射右美托咪定用于阻生第三磨牙拔除术患者清醒镇静的疗效:一项双盲、半口对照研究
J Maxillofac Oral Surg. 2016 Dec;15(4):512-516. doi: 10.1007/s12663-016-0889-3. Epub 2016 Apr 21.
5
Comparison between intranasal dexmedetomidine and intranasal ketamine as premedication for procedural sedation in children undergoing MRI: a double-blind, randomized, placebo-controlled trial.鼻内给予右美托咪定与鼻内给予氯胺酮作为接受MRI检查儿童程序性镇静术前用药的比较:一项双盲、随机、安慰剂对照试验。
J Anesth. 2014 Feb;28(1):12-8. doi: 10.1007/s00540-013-1657-x. Epub 2013 Jun 26.