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[因急性呼吸道疾病入住呼吸科的男性患者静脉血栓栓塞症的发病率]

[Incidence of venous thromboembolism in men admitted to a pneumology unit for acute respiratory disease].

作者信息

Aissa I, Rachdi I, Ben Miled K, Ghedira H

机构信息

Service de pneumologie I, Pavillon I, hôpital Abderrahman Mami, Ariana, Tunisie. imen

出版信息

Rev Pneumol Clin. 2011 Jun;67(3):129-35. doi: 10.1016/j.pneumo.2010.04.003. Epub 2010 Nov 30.

DOI:10.1016/j.pneumo.2010.04.003
PMID:21665075
Abstract

BACKGROUND

Venous thromboembolism (VTE) is a major source of morbidity and mortality all over the world. It is one of the complications arising in a hospital environment. The main aim of this study is to estimate the incidence of VTE in respiratory inpatients.

METHOD

The authors carried out a prospective study on acute respiratory disease inpatients. A medical analytical index card was used. An echo-venous Doppler of lower limbs was practiced on D1 and D10 of hospitalization. The Wells scored was used to estimate the clinical probability of the occurrence of VTE.

RESULTS

Seven of 100 patients studied developed VTE (95% CI : 2-12%), four of which presented a pulmonary embolism. The patients with VTE are 60-years-old±11.67. The incidence of VTE includes 20% (95% CI : 12.2-27.8%) of the patients hospitalized for bronchial cancer, 7.14% (95% CI : 2.1-12.18) of the patients presenting pulmonary tuberculosis and 4.54% (95% CI : 0.46-8.62%) of the patients hospitalized for exacerbation of chronic obstructive pulmonary disease (COPD). The duration of hospitalization was prolonged for the treatment of VTE (21±4.41 days for these patients compared with 12±5 days in the absence of VTE (P<0.001)). The analysis of the various risk factors shows that a Performance Status>2 (P=0.005) and lung cancer (P=0.028) are the factors most incriminated in the occurrence of VTE. It is associated with a mortality of 2%.

CONCLUSION

VTE is a reality which is necessary to prevent in respiratory inpatients in situations at risk, especially in patients with lung cancer and with a PS>2.

摘要

背景

静脉血栓栓塞症(VTE)是全球发病和死亡的主要原因之一。它是医院环境中出现的并发症之一。本研究的主要目的是评估呼吸内科住院患者中VTE的发生率。

方法

作者对急性呼吸道疾病住院患者进行了一项前瞻性研究。使用了医学分析索引卡。在住院第1天和第10天对下肢进行静脉多普勒超声检查。采用Wells评分来评估VTE发生的临床可能性。

结果

在研究的100例患者中,有7例发生了VTE(95%可信区间:2%-12%),其中4例出现肺栓塞。发生VTE的患者年龄为60岁±11.67岁。VTE的发生率在因支气管癌住院的患者中为20%(95%可信区间:12.2%-27.8%),在患有肺结核的患者中为7.14%(95%可信区间:2.1%-12.18%),在因慢性阻塞性肺疾病(COPD)加重住院的患者中为4.54%(95%可信区间:0.46%-8.62%)。因VTE治疗住院时间延长(这些患者为21±4.41天,而无VTE患者为12±5天,P<0.001)。对各种危险因素的分析表明,体能状态>2(P=0.005)和肺癌(P=0.028)是VTE发生最主要的因素。其死亡率为2%。

结论

VTE是一个现实问题,对于处于危险情况的呼吸内科住院患者,尤其是肺癌患者和体能状态>2的患者,必须加以预防。

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