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手性协同催化三组分反应中芳基重氮乙酸酯、醇和β,γ-不饱和α-酮酯的立体选择性转换。

Diastereoselectivity switch in cooperatively catalyzed three-component reactions of an aryldiazoacetate, an alcohol, and a β,γ-unsaturated α-keto ester.

机构信息

Department of Chemistry, East China Normal University, Shanghai, People's Republic of China.

出版信息

J Org Chem. 2011 Jul 15;76(14):5821-4. doi: 10.1021/jo102423c. Epub 2011 Jun 13.

DOI:10.1021/jo102423c
PMID:21667947
Abstract

A highly switchable,diastereoselectivity-controlled, three-component reaction of aryldiazoacetate, alcohol,and β,γ-unsaturated α-keto esters has been achieved through a dual-metal cooperative catalysis strategy.

摘要

通过双金属协同催化策略，实现了高可切换、非对映选择性控制的芳基重氮乙酸酯、醇和β,γ-不饱和α-酮酯的三组分反应。

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