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新型无柄髋关节植入物(Proxima 与 Nanos)的骨整合:DXA 研究:初步结果。

Bone integration of new stemless hip implants (proxima vs. nanos). A DXA study: preliminary results.

机构信息

Department of Ortopaedics, Catholic University of Rome-Policlinico A. Gemelli, Rome, Italy.

出版信息

Int J Immunopathol Pharmacol. 2011 Jan-Mar;24(1 Suppl 2):113-6. doi: 10.1177/03946320110241S221.

Abstract

The development of short femoral prostheses has the advantage to preserve bone and soft tissues, restore hip geometry, permit mini-invasive techniques and allow quickly return to an active life, but very few studies described bone reaction to these new designed prostheses. The aim of the present study was to evaluate the osseointegration of two different partial neck retained stemless hip prosthesis at one year after surgery, measured by the changes of periprosthetic bone mineral density (BMD) in 5 regions of interest (ROIs) using a dual-energy X ray absorptiometry (DXA) device. The signs of stress-shielding were evaluated by standard radiographs. Thirty-two uncemented primary total hip arthroplasty (THA) patients allocated into 2 groups were evaluated. In the first group (n=19) a Proxima (De-Puy-J&J) hip stem was implanted. In the second group (n=12) a Nanos (Smith & Nephew) hip stem was used. We found that both the implants preserve metaphyseal bone stock and increase periprosthetic BMD. In Nanos prostheses a significant higher BMD values were observed in region of interest (ROI) 3 and 4 (p<0.05). No differences were found in ROIs 1, 2, and 5. Proxima stem seem to produce a physiological strain distribution in the femur. No signs of stress-shielding were present in both the implants. In conclusion, this preliminary DXA analysis showed a physiological integration of both the stems that reproduces the biomechanical stress of proximal femur. New designed short stem implants showed optimal osseointegration after one year, and therefore appears an excellent alternative to traditional long stem hip prostheses.

摘要

短柄股骨假体的发展具有保留骨和软组织、恢复髋关节几何形状、允许微创技术以及快速恢复活跃生活的优势,但很少有研究描述这些新设计假体的骨反应。本研究的目的是通过双能 X 射线吸收仪 (DXA) 设备在 5 个感兴趣区域 (ROI) 测量假体周围骨矿物质密度 (BMD) 的变化,评估两种不同的保留部分颈干的无柄髋关节假体在手术后 1 年的骨整合情况。通过标准射线照相评估应力遮挡的迹象。对 32 例未固定的原发性全髋关节置换术 (THA) 患者进行评估,分为 2 组。第 1 组 (n=19) 植入 Proxima (De-Puy-J&J) 髋关节假体。第 2 组 (n=12) 植入 Nanos (Smith & Nephew) 髋关节假体。我们发现,两种植入物都保留了骨干骨量并增加了假体周围的 BMD。在 Nanos 假体中,在 ROI 3 和 4 观察到显著更高的 BMD 值 (p<0.05)。在 ROI 1、2 和 5 未发现差异。Proxima 假体似乎在股骨中产生了生理应变分布。两种假体均未出现应力遮挡迹象。总之,初步的 DXA 分析表明,两种假体均实现了生理整合,再现了股骨近端的生物力学应力。新设计的短柄植入物在 1 年后显示出了最佳的骨整合,因此似乎是传统长柄髋关节假体的极佳替代品。

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