Hu Liang-ping, Bao Xiao-lei, Wang Qi
Consulting Center of Biomedical Statistics, Academy of Military Medical Sciences, Beijing 100850, China.
Zhong Xi Yi Jie He Xue Bao. 2011 Jun;9(6):592-5. doi: 10.3736/jcim20110603.
Scientific research design includes specialty design and statistics design which can be subdivided into experimental design, clinical trial design and survey design. Usually, statistics textbooks introduce the core aspects of experimental design as the three key elements, the four principles and the design types, which run through the whole scientific research design and determine the overall success of the research. This article discusses the principle of randomization, which is one of the four principles, and focuses on the following two issues--the definition and function of randomization and the real life examples which go against the randomization principle, thereby demonstrating that strict adherence to the randomization principle leads to meaningful and valuable scientific research.
科学研究设计包括专业设计和统计设计，其中统计设计又可细分为实验设计、临床试验设计和调查设计。通常，统计学教材将实验设计的核心内容介绍为三个关键要素、四个原则和设计类型，这些贯穿于整个科学研究设计过程，并决定研究的整体成败。本文讨论了四个原则之一的随机化原则，并重点关注以下两个问题——随机化的定义和作用以及违背随机化原则的实际例子，从而证明严格遵守随机化原则会带来有意义且有价值的科学研究。
