对照临床试验中的随机化方法。

Methods of randomization in controlled clinical trials.

作者信息

Moeschberger M L, Williams J A, Brown C G

出版信息

Am J Emerg Med. 1985 Sep;3(5):467-73. doi: 10.1016/0735-6757(85)90207-4.

Abstract

In this second article of a series that explores design and analysis issues in controlled clinical trials in emergency medicine, we have discussed the case for randomization, reviewed the methods involved in simple randomization, highlighted some of the practical problems involved with randomization, and presented some modified randomization schemes intended to remedy these problems.

摘要

在本系列探讨急诊医学对照临床试验设计与分析问题的第二篇文章中，我们讨论了随机化的理由，回顾了简单随机化所涉及的方法，强调了随机化所涉及的一些实际问题，并提出了一些旨在解决这些问题的改良随机化方案。