McCombe A, Lund V J, Howard D J
Institute of Laryngology and Otology, London, United Kingdom.
Rhinology. 1990 Jun;28(2):97-102.
A potential for recurrence of juvenile angiofibroma exists after all treatment modalities, both surgical and medical but the methods of defining recurrence and failure to cure varies considerably from series to series. To evaluate factors which might influence successful treatment, a series of 33 patients have been reviewed retrospectively. All patients were treated by simple or extended lateral rhinotomy as a primary or secondary procedure. The final long-term disease control rate was 97% but during the treatment period the overall symptomatic recurrence rate was 50%. However, amongst those treated primarily the recurrence rate was 34%. Of the factors examined, the strongest predictor of recurrence was preoperative embolisation. This group exhibited both early and multiple recurrence when compared with the non-embolised group and the possible reasons for this are examined.
无论采用手术还是药物等何种治疗方式，青少年血管纤维瘤均有复发的可能，但不同研究系列中定义复发和治疗失败的方法差异很大。为评估可能影响治疗成功的因素，对33例患者进行了回顾性分析。所有患者均接受单纯或扩大外侧鼻切开术，作为初次或二次手术。最终长期疾病控制率为97%，但在治疗期间总体症状复发率为50%。然而，初次接受治疗的患者中复发率为34%。在所研究的因素中，复发的最强预测因素是术前栓塞。与未栓塞组相比，该组出现了早期和多次复发，并对其可能原因进行了探讨。
