Developmental Pediatrics, Mubarak Al-Kabeer Hospital, Kuwait City, Kuwait.
Pediatrics. 2011 Jul;128(1):e211-7. doi: 10.1542/peds.2010-1881. Epub 2011 Jun 13.
BACKGROUND. Autism is a serious neurodevelopmental disorder that has a reportedly rising prevalence rate. The American Academy of Pediatrics recommends that screening for autism be incorporated into routine practice. It is important to consider the pros and cons of conducting autism screening as part of routine practice and its implications on the community. We have explored this question in the context of screening from a scientific point of view.
A literature search was conducted to assess the effectiveness of community screening programs for autism.
Judged against critical questions about autism, screening programs failed to fulfill most criteria. Good screening tools and efficacious treatment are lacking, and there is no evidence yet that such a program would do more good than harm.
On the basis of the available research, we believe that we do not have enough sound evidence to support the implementation of a routine population-based screening program for autism. Ongoing research in this field is certainly needed, including the development of excellent screening instruments and demonstrating with clinical trials that such programs work and do more good than harm.
自闭症是一种严重的神经发育障碍，其发病率据报道呈上升趋势。美国儿科学会建议将自闭症筛查纳入常规实践。考虑到在常规实践中进行自闭症筛查的利弊及其对社区的影响非常重要。我们从科学的角度在自闭症筛查的背景下探讨了这个问题。
进行了文献检索，以评估自闭症社区筛查计划的有效性。
根据自闭症的关键问题进行判断，筛查计划未能满足大多数标准。缺乏良好的筛查工具和有效的治疗方法，而且还没有证据表明这样的计划会带来更多的好处而不是危害。
根据现有研究，我们认为我们没有足够可靠的证据来支持实施自闭症常规人群筛查计划。当然，该领域还需要开展更多的研究，包括开发优秀的筛查工具，并通过临床试验证明此类计划有效且带来的好处多于危害。
