Hosokawa Y, Suzuki H, Nishikimi M, Matsukage A, Yoshida M C, Ozawa T
Department of Biomedical Chemistry, Faculty of Medicine, University of Nagoya, Japan.
Biochem Int. 1990;21(1):41-4.
The ubiquinone-binding protein (QP-C) is a nuclear-encoded subunit of the cytochrome bc1 complex in the mitochondrial respiratory chain and is thought to be involved in the electron transfer reaction coupled to energy transduction. We recently isolated a nuclear gene for human QP-C and used, in the present study, its fragment as a probe for Southern blot analysis of EcoRI-digested DNAs prepared from 14 human-mouse somatic cell hybrids. The results indicated that the human QP-C gene is located on chromosome 8.
