T11（CD2）基因在人类中定位于1号染色体，在小鼠中定位于3号染色体。
The gene for T11 (CD2) maps to chromosome 1 in humans and to chromosome 3 in mice.
作者信息
Clayton L K, Ramachandran H, Pravtcheva D, Chen Y F, Diamond D J, Ruddle F H, Reinherz E L
机构信息
Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA 02115.
出版信息
J Immunol. 1988 May 15;140(10):3617-21.
The chromosomal locations of the human and murine T11 (CD2) gene have been determined. Using recently cloned cDNA to probe Southern blots of mouse X human and Chinese hamster X mouse somatic cell hybrids, we have localized the human T11 gene to chromosome 1 and the murine T11 gene to chromosome 3. Based on previously determined blocks of homology between human chromosome 1 and mouse chromosome 3, it is suggested that the human T11 gene may lie on the short arm of chromosome 1 proximal to p221. Thus, the T11 gene is not linked to any other genes for T cell markers that have been mapped to date.
人类和鼠类T11（CD2）基因的染色体定位已经确定。利用最近克隆的cDNA探测小鼠×人及中国仓鼠×小鼠体细胞杂种的Southern印迹，我们已将人类T11基因定位于1号染色体，将鼠类T11基因定位于3号染色体。根据先前确定的人类1号染色体和小鼠3号染色体之间的同源区域，提示人类T11基因可能位于1号染色体短臂上靠近p221的位置。因此，T11基因与迄今已定位的任何其他T细胞标志物基因均无连锁关系。
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