Nishikimi M, Suzuki H, Yamaguchi M, Matsukage A, Yoshida M C, Ozawa T
Department of Biomedical Chemistry, Faculty of Medicine, University of Nagoya, Japan.
Biochem Int. 1988 Apr;16(4):655-60.
We previously isolated a cDNA clone for human cytochrome c1. The insert DNA of approximately 950 bp from this clone was used as a probe to identify the cytochrome c1 gene. High molecular weight DNAs extracted from a panel of 14 independent human-mouse somatic cell hybrids were digested with BamHI and analyzed by Southern blot hybridization. The results indicated that the gene for human cytochrome c1 is located on chromosome 8.
我们之前分离出了人类细胞色素c1的一个cDNA克隆。用来自该克隆的约950 bp的插入DNA作为探针来鉴定细胞色素c1基因。从一组14个独立的人-鼠体细胞杂种中提取的高分子量DNA用BamHI进行消化，并通过Southern印迹杂交进行分析。结果表明，人类细胞色素c1基因位于8号染色体上。
