Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Diabet Med. 2011 Oct;28(10):1268-71. doi: 10.1111/j.1464-5491.2011.03357.x.
To determine whether improvements in glucose regulation following the PREPARE structured education programme were sustained at 24 months.
Ninety-eight overweight or obese individuals with impaired glucose tolerance were randomized to receive: (1) advice leaflet, (2) 3-h structured education programme aimed at promoting physical activity, (iii) 3-h structured education with personalized pedometer use. The primary outcome was change in 2-h post-challenge plasma glucose.
Seventy-three (74%) individuals were included for analysis at 24 months; age 65 ± 8 years, BMI 29.3 ± 4.8 kg/m(2), South Asian ethnicity 21%. A statistically significant reduction in 2-h glucose of -1.6 mmol/l (-0.4 to -2.7) was seen in the education-with-pedometer group compared with the control group. There is no significant difference in the education-only group.
Improvements in glucose regulation following a pragmatic group-based structured education with pedometer use were sustained at 24 months.
确定 PREPARE 结构化教育计划改善血糖调节的效果是否能持续到 24 个月。
98 名超重或肥胖、糖耐量受损的个体被随机分为三组：（1）接受建议传单，（2）3 小时结构化教育计划，旨在促进体力活动，（3）3 小时结构化教育，个性化计步器使用。主要结局指标是 2 小时餐后血糖的变化。
73 名（74%）个体在 24 个月时纳入分析；年龄 65±8 岁，BMI 29.3±4.8kg/m(2)，南亚裔 21%。与对照组相比，计步器组的 2 小时血糖降低了-1.6mmol/l（-0.4 至-2.7），有统计学意义。在仅接受教育组没有显著差异。
使用计步器的基于群体的实用结构化教育，改善血糖调节的效果能持续到 24 个月。
