Abe Takashi, Kawakami Yasuo, Kondo Masakatsu, Fukunaga Tetsuo
Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Japan.
Clin Physiol Funct Imaging. 2011 Jul;31(4):320-5. doi: 10.1111/j.1475-097X.2011.01021.x. Epub 2011 Mar 21.
The purpose of this study was to compare the age-related muscle loss in both the appendicular and trunk regions in 207 Japanese and 111 German men aged 20-62 years. Ultrasound-measured muscle thickness (MTH) was taken at eight sites from the anterior and posterior aspects of the body, and the MTH was expressed in terms relative to limb length (MTH/L) or standing height (MTH/Ht). In both the Japanese and Germans, age was correlated with quadriceps MTH (Japanese, r = -0·347; Germans, r = -0·292; both P<0·01) and abdomen MTH (Japanese, r = -0·300, P<0·01; Germans, r = -0·232; P<0·05). On the other hand, hamstring MTH was correlated with age in the Japanese (r = -0·188, P<0·01), but not in the Germans (r = 0·100). There were no significant correlations between age and other limb (i.e. triceps surae MTH/L, Japanese, r = 0·04; Germans, r = 0·05) and trunk sites (subscapula MTH/Ht, Japanese, r = -0·09; Germans, r = -0·02). In conclusion, age-related skeletal muscle loss was strongly observed in the quadriceps and abdominal sites in both the Japanese and German men, although the rate of regular physical activity was different between the two groups.
本研究旨在比较207名年龄在20至62岁之间的日本男性和111名德国男性在四肢和躯干区域与年龄相关的肌肉流失情况。通过超声测量身体前后八个部位的肌肉厚度（MTH），并将MTH表示为相对于肢体长度（MTH/L）或身高（MTH/Ht）的相对值。在日本人和德国人中，年龄与股四头肌MTH均相关（日本人，r = -0·347；德国人，r = -0·292；P均<0·01）以及与腹部MTH相关（日本人，r = -0·300，P<0·01；德国人，r = -0·232；P<0·05）。另一方面，在日本人中，绳肌MTH与年龄相关（r = -0·188，P<0·01），但在德国人中不相关（r = 0·100）。年龄与其他肢体部位（即比目鱼肌MTH/L，日本人，r = 0·04；德国人，r = 0·05）和躯干部位（肩胛下肌MTH/Ht，日本人，r = -0·09；德国人，r = -0·02）之间均无显著相关性。总之，尽管两组之间的规律体育活动率不同，但在日本男性和德国男性中，均强烈观察到股四头肌和腹部部位存在与年龄相关的骨骼肌流失。
