Abe Takashi, Loenneke J P, Thiebaud R S, Ogawa M, Mitsukawa N
Indiana University Department of Kinesiology, School of Public Health 1025 East 7th Street, Room 104 Bloomington IN 47405 USA Toyo Gakuen University Active Aging Research Center Nagareyama, Chiba Japan.
University of Oklahoma Department of Health and Exercise Science Norman OK USA.
Acta Physiol Hung. 2014 Dec;101(4):488-95. doi: 10.1556/APhysiol.101.2014.006.
To investigate the relationships between site-specific muscle loss in the thigh, muscle quality and zigzag walking performance, 40 men and 41 women aged 65-79 years had muscle thickness (MTH) measured by ultrasound at nine sites on the anterior and posterior aspects of the body. Skeletal muscle mass (SM) was estimated from an ultrasound-derived prediction equation. Site-specific thigh sarcopenia was calculated using ultrasound-measured MTH at the anterior/posterior aspects of the thigh (AP-MTH ratio). Zigzag walking time (ZWT) and maximum isometric knee extension (KE) and flexion (KF) torques were measured. Muscle quality (torque/thigh SM) and knee joint strength index (torque/body mass) were calculated. There were no significant correlations between SM index and ZWT. However, AP-MTH ratio was inversely correlated (P < 0.05) to ZWT in men (r = -0.335) and women (r = -0.309). ZWT was also inversely correlated (P < 0.05) to KE-strength index in both sexes (men, r = -0.328; women, r = -0.372). Similarly, ZWT was correlated to KF-strength index (r = -0.497) and muscle quality (r = -0.322) in women, but not in men. After adjusting for age, height and body mass, AP-MTH ratio was inversely correlated to ZWT in men (r = -0.325) and tended to be correlated to ZWT in women (r = -0.263). Zigzag walking performance may be associated with site-specific thigh sarcopenia in older men and women.
为了研究大腿特定部位的肌肉流失、肌肉质量与之字形行走表现之间的关系，对40名年龄在65 - 79岁的男性和41名女性进行了研究，通过超声测量身体前后九个部位的肌肉厚度（MTH）。根据超声衍生的预测方程估算骨骼肌质量（SM）。使用超声测量的大腿前后侧MTH（AP - MTH比值）计算特定部位的大腿肌肉减少症。测量之字形行走时间（ZWT）以及最大等长膝关节伸展（KE）和屈曲（KF）扭矩。计算肌肉质量（扭矩/大腿SM）和膝关节强度指数（扭矩/体重）。SM指数与ZWT之间无显著相关性。然而，AP - MTH比值在男性（r = - 0.335）和女性（r = - 0.309）中与ZWT呈负相关（P < 0.05）。ZWT在男女两性中与KE强度指数也呈负相关（P < 0.05）（男性，r = - 0.328；女性，r = - 0.372）。同样，ZWT在女性中与KF强度指数（r = - 0.497）和肌肉质量（r = - 0.322）相关，但在男性中不相关。在调整年龄、身高和体重后，AP - MTH比值在男性中与ZWT呈负相关（r = - 0.325），在女性中与ZWT呈倾向相关性（r = - 0.263）。之字形行走表现可能与老年男性和女性特定部位的大腿肌肉减少症有关。
