Kubota Suguru, Sugiki Hiroshi, Wakasa Satoru, Ooka Tomonori, Tachibana Tsuyoshi, Sasaki Shigeyuki, Matsui Yoshiro
Department of Cardiovascular Surgery, Hokkaido University Hospital, Kita-14, Nishi-5, Kita-ku, Sapporo 060-8648, Japan.
Gen Thorac Cardiovasc Surg. 2011 Jun;59(6):406-12. doi: 10.1007/s11748-010-0770-0. Epub 2011 Jun 15.
After radiofrequency (RF) ablation became available, the indication of MAZE procedure conducted with bipolar RF was expanded. We examined the efficacy and feasibility of the RF MAZE procedure in valve surgery and identified the predictors of atrial fibrillation (AF) recurrence.
Forty-four patients had permanent AF at the time of operation and underwent a biatrial RF MAZE procedure. Univariate and multivariate analysis for the predictor of permanent AF recurrence and follow-up studies were performed.
Of the patients, 37 (84.1%) were in non-AF rhythm at discharge and 25 (80.6%) were at the latest follow-up (mean, 2.1 ± 1.2 years). In stepwise multivariate analysis, left atrial dimension (LAD) > 61.5 mm was an independent predictor of early-term recurrence of AF (P = 0.006) and late-term recurrence (P = 0.038) as well. F-wave voltage <0.1 mV was significant in univariate analysis but was not significant in multivariate analysis for predictor of late-term AF recurrence. Avoidance of AF in the late term was 56% for LAD > 60 mm whereas it was 91% for LAD ≤ 60 mm (P = 0.043), 67% for F-wave < 0.1 mV compared to 100% for F-wave ≥ 0.1 mV (P = 0.031), and 43% for LAD > 60 mm and F-wave < 0.1 mV compared to 91% for LAD ≤ 60 mm and/or F-wave ≥ 0.1 mV (P = 0.016), respectively. Although avoidance of AF in the late term was lower in patients with LAD > 60 mm or F-wave < 0.1 mV, more than half of these patients were free from AF in the late term.
LA size was assumed to be a simple and strong predictor of recurrent AF in this procedure. Predictive criteria that had been widely employed for the "cut-and-sew" MAZE procedure accompanied with valve surgery can be expanded in the MAZE procedure with RF devices.
在射频(RF)消融技术出现后,双极射频迷宫手术的适应证得以扩大。我们研究了射频迷宫手术在瓣膜手术中的疗效和可行性,并确定了心房颤动(AF)复发的预测因素。
44例患者在手术时患有永久性房颤,接受了双心房射频迷宫手术。对永久性房颤复发的预测因素进行单因素和多因素分析,并进行随访研究。
患者中,37例(84.1%)出院时处于非房颤心律,25例(80.6%)在最近一次随访时(平均2.1±1.2年)仍保持非房颤心律。在逐步多因素分析中,左心房内径(LAD)>61.5mm是房颤早期复发(P=0.006)和晚期复发(P=0.038)的独立预测因素。F波电压<0.1mV在单因素分析中有意义,但在多因素分析中对晚期房颤复发的预测因素无意义。LAD>60mm的患者晚期无房颤的比例为56%,而LAD≤60mm的患者为91%(P=0.043);F波<0.1mV的患者为67%,而F波≥0.1mV的患者为100%(P=0.031);LAD>60mm且F波<0.1mV的患者为43%,而LAD≤60mm和/或F波≥0.1mV的患者为91%(P=0.016)。尽管LAD>60mm或F波<0.1mV的患者晚期无房颤的比例较低,但这些患者中仍有超过一半在晚期无房颤。
在该手术中,左心房大小被认为是房颤复发的一个简单而有力的预测因素。在瓣膜手术中广泛应用于“切割缝合”迷宫手术的预测标准可在射频设备的迷宫手术中扩展。