Eitrem R, Vene S, Niklasson B
National Bacteriological Laboratory, Stockholm, Sweden.
Am J Trop Med Hyg. 1990 Aug;43(2):207-11. doi: 10.4269/ajtmh.1990.43.207.
Members of a Swedish United Nations (UN) battalion of 362 soldiers were bled just before and immediately after their 6 month tour of duty in Cyprus during 1985. Sera were tested for presence of specific antibodies to sand fly fever (SF) Sicilian, SF Naples, and Toscana viruses by both indirect immunofluorescence antibody test (IFT) and plaque reduction neutralization test (PRNT). Of 298 serum pairs available, seroconversion was noted in 11 soldiers: 7 cases for SF Sicilian, 3 for SF Naples, and 1 for Toscana virus. IFT and PRNT revealed identical results. Seroconversion was associated with clinical disease in 7 out of 7, 2 out of 3, and 0 out of 1 for SF Sicilian, SF Naples, and Toscana infections, respectively. Virus isolation was attempted on acute-phase sera collected from febrile patients. Of 5 such acute-phase sera from patients with serologically verified SF, virus was recovered from 2: 1 strain of SF Sicilian virus and 1 strain of SF Naples virus.
1985年，瑞典一支由362名士兵组成的联合国营的成员在塞浦路斯执行为期6个月的任务之前和刚结束任务后接受了采血。通过间接免疫荧光抗体试验（IFT）和蚀斑减少中和试验（PRNT）检测血清中是否存在针对白蛉热（SF）西西里病毒、SF那不勒斯病毒和托斯卡纳病毒的特异性抗体。在298对可用血清中，11名士兵出现了血清转化：7例为SF西西里病毒，3例为SF那不勒斯病毒，1例为托斯卡纳病毒。IFT和PRNT结果一致。对于SF西西里病毒感染，7例血清转化者中有7例出现临床疾病；对于SF那不勒斯病毒感染，3例中有2例出现临床疾病；对于托斯卡纳病毒感染，1例血清转化者中无临床疾病出现。尝试从发热患者急性期血清中分离病毒。在5份血清学确诊为SF的患者急性期血清中，2份病毒分离成功：1份为SF西西里病毒株，1份为SF那不勒斯病毒株。
