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甲状腺功能对一个种族多样化的农村女性样本认知的影响:FRONTIER 项目研究。

The influence of thyroid function on cognition in a sample of ethnically diverse, rural-dwelling women: a project FRONTIER study.

机构信息

Laura W. Bush Institute for Women's Health, Texas Tech University Health Sciences Center, Amarillo; Department of Family and Community Medicine, Texas Tech University Health Sciences Center, Lubbock; Department of Psychology, Texas Tech University, Lubbock, TX, USA.

出版信息

J Neuropsychiatry Clin Neurosci. 2011 Spring;23(2):219-22. doi: 10.1176/jnp.23.2.jnp219.

Abstract

This study examined the influence of thyroid markers (TSH and FT4) on cognition in a sample of rural-dwelling women. Data were analyzed from 81 women who were enrolled in an ongoing study of rural health, Project FRONTIER. Cognition was assessed with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). TSH levels were significantly related to the RBANS Attention Index, and FT4 levels were significantly related to the RBANS Language Index. The current study found that TSH and FT4 were differentially related to neurocognitive domains, with TSH being related only to measures of attention and FT4 to measures of language.

摘要

本研究考察了甲状腺标志物(TSH 和 FT4)对农村女性认知的影响。数据来自于 81 名参与农村健康项目 FRONTIER 的女性。认知评估采用重复性成套神经心理状态测验(RBANS)。TSH 水平与 RBANS 注意力指数显著相关,FT4 水平与 RBANS 语言指数显著相关。本研究发现,TSH 和 FT4 与神经认知领域存在差异相关,TSH 仅与注意力相关,FT4 仅与语言相关。

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